PDBe 2a4j

Solution NMR

Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Centrin-2 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P41208 (Residues: 94-172; Coverage: 46%)
Gene names: CALT, CEN2, CETN2
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
DNA repair protein complementing XP-C cells Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 2.11 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q01831 (Residues: 847-863; Coverage: 2%)
Gene names: XPC, XPCC

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 70%
Refinement method: simulated annealing
Chemical shifts: BMR5992  
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided