PDBe 2a38

X-ray diffraction
2Å resolution

Crystal structure of the N-Terminus of titin


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Titin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 194 amino acids
Theoretical weight: 20.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q8WZ42 (Residues: 1-194; Coverage: 1%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P1
Unit cell:
a: 55.406Å b: 56.294Å c: 74.414Å
α: 71.96° β: 88.49° γ: 75.41°
R R work R free
0.209 0.209 0.255
Expression system: Escherichia coli BL21(DE3)