PDBe 1zuz

X-ray diffraction
1.91Å resolution

Calmodulin in complex with a mutant peptide from human DRP-1 kinase

Released:
Source organism: Homo sapiens
Entry authors: Kursula P, Vahokoski J, Wilmanns M

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 Chain: A
Molecule details ›
Chain: A
Length: 150 amino acids
Theoretical weight: 16.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP24 (Residues: 1-149; Coverage: 100%)
Gene names: CALM2, CAM2, CAMB
Death-associated protein kinase 2 Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UIK4 (Residues: 312-330; Coverage: 5%)
Gene name: DAPK2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 66.52Å b: 34.03Å c: 73.85Å
α: 90° β: 109.58° γ: 90°
R-values:
R R work R free
0.194 0.191 0.248
Expression systems:
  • Escherichia coli
  • Not provided