› › Structure analysis

Cyrstal Structure of Human Cyclophilin-A in Complex with suc-AGPF-pNA

X-ray diffraction
2.55Å resolution
PDB entry 1zkf coloured by chain, front view.
PDB entry 1zkf coloured by chain, side view.
PDB entry 1zkf coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Peptidyl-prolyl cis-trans isomerase A and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 7609.67 Å2
Buried surface area: 1142.49 Å2
Dissociation area: 457 Å2
Dissociation energy (ΔGdiss): -6.42 kcal/mol
Dissociation entropy (TΔSdiss): 6.1 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158789
Assembly 2
Download    3D Visualisation
Assembly Name: Peptidyl-prolyl cis-trans isomerase A and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 7627.61 Å2
Buried surface area: 1155.77 Å2
Dissociation area: 459.56 Å2
Dissociation energy (ΔGdiss): -6.32 kcal/mol
Dissociation entropy (TΔSdiss): 6.08 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158789

Macromolecules

Peptidyl-prolyl cis-trans isomerase A
Chains: A, B
Length: 165 amino acids
Theoretical weight: 18.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62937 (Residues: 1-165; Coverage: 100%)
Gene names: CYPA, PPIA
Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
InterPro:
CATH: Cyclophilin-like
SCOP: Cyclophilin (peptidylprolyl isomerase)
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1zkf, assembly 1, front view.
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1zkf, assembly 1, side view.
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1zkf, assembly 1, top view.
Molecule details ›

Search similar proteins

Suc-ALA-GLY-PRO-PHE-pNA
Chains: C, D
Length: 6 amino acids
Theoretical weight: 611 Da
Source organism: Homo sapiens
Expression system: Not provided
Suc-ALA-GLY-PRO-PHE-pNA in PDB entry 1zkf, assembly 1, front view.
Suc-ALA-GLY-PRO-PHE-pNA in PDB entry 1zkf, assembly 1, side view.
Suc-ALA-GLY-PRO-PHE-pNA in PDB entry 1zkf, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links