PDBe 1zj8

X-ray diffraction
2.8Å resolution

Structure of Mycobacterium tuberculosis NirA protein


Function and Biology Details

Reaction catalysed:
Hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H(2)O = sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H(+)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Sulfite reductase [ferredoxin] Chains: A, B
Molecule details ›
Chains: A, B
Length: 566 amino acids
Theoretical weight: 63.49 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P9WJ03 (Residues: 3-555; Coverage: 100%)
Gene names: Rv2391, nirA, sir
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P212121
Unit cell:
a: 84.257Å b: 115.355Å c: 114.697Å
α: 90° β: 90° γ: 90°
R R work R free
0.219 0.215 0.292
Expression system: Escherichia coli BL21(DE3)