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PHOSPHOTRANSFERASE

Source organism: Geobacillus stearothermophilus
Biochemical function: nucleoside monophosphate kinase activity
Biological process: organonitrogen compound biosynthetic process
Cellular component: cytosol

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EC 2.7.4.3: Adenylate kinase

Reaction catalysed:
ATP + AMP = 2 ADP
Systematic name:
ATP:AMP phosphotransferase
Alternative Name(s):
  • 5'-AMP-kinase
  • Adenylic kinase
  • Adenylokinase
  • Myokinase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF05191
Domain description: Adenylate kinase, active site lid
Occurring in:
  1. Adenylate kinase
The deposited structure of PDB entry 1zio contains 1 copy of Pfam domain PF05191 (Adenylate kinase, active site lid) in Adenylate kinase. Showing 1 copy in chain A.

PF00406
Domain description: Adenylate kinase
Occurring in:
  1. Adenylate kinase
The deposited structure of PDB entry 1zio contains 1 copy of Pfam domain PF00406 (Adenylate kinase) in Adenylate kinase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000850
Domain description: Adenylate kinase/UMP-CMP kinase
Occurring in:
  1. Adenylate kinase
IPR007862
Domain description: Adenylate kinase, active site lid domain
Occurring in:
  1. Adenylate kinase
IPR033690
Domain description: Adenylate kinase, conserved site
Occurring in:
  1. Adenylate kinase
IPR006259
Domain description: Adenylate kinase subfamily
Occurring in:
  1. Adenylate kinase
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Adenylate kinase

Structure domain

CATH CATH domain
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Adenylate kinase
The deposited structure of PDB entry 1zio contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Adenylate kinase. Showing 1 copy in chain A.
SCOP SCOP annotations
52541
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Adenylate kinase
The deposited structure of PDB entry 1zio contains 1 copy of SCOP domain 52541 (Nucleotide and nucleoside kinases) in Adenylate kinase. Showing 1 copy in chain A.
57775
Class: Small proteins
Fold: Rubredoxin-like
Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain
Occurring in:
  1. Adenylate kinase
The deposited structure of PDB entry 1zio contains 1 copy of SCOP domain 57775 (Microbial and mitochondrial ADK, insert in Adenylate kinase. Showing 1 copy in chain A.">

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