PDBe 1zdt

X-ray diffraction
2.1Å resolution

The Crystal Structure of Human Steroidogenic Factor-1


Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Steroidogenic factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 241 amino acids
Theoretical weight: 27.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q13285 (Residues: 221-461; Coverage: 52%)
Gene names: AD4BP, FTZF1, NR5A1, SF1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Nuclear receptor coactivator 2 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 12 amino acids
Theoretical weight: 1.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q15596 (Residues: 741-752; Coverage: 1%)
Gene names: BHLHE75, NCOA2, SRC2, TIF2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3121
Unit cell:
a: 73.601Å b: 73.601Å c: 195.678Å
α: 90° β: 90° γ: 120°
R R work R free
0.218 0.216 0.265
Expression systems:
  • Escherichia coli
  • Not provided