PDBe 1zc0

X-ray diffraction
1.85Å resolution

Crystal structure of human hematopoietic tyrosine phosphatase (HePTP) catalytic domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 7 Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 35.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35236 (Residues: 64-360; Coverage: 83%)
Gene name: PTPN7
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P61
Unit cell:
a: 127.101Å b: 127.101Å c: 59.863Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.163 0.161 0.186
Expression system: Escherichia coli