PDBe 1z4y

X-ray diffraction
2.6Å resolution

Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin-neuraminidase Chain: A
Molecule details ›
Chain: A
Length: 532 amino acids
Theoretical weight: 58.51 KDa
Source organism: Mammalian rubulavirus 5
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P04850 (Residues: 37-565; Coverage: 94%)
Gene name: HN
Structure domains: Neuraminidase

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: P6122
Unit cell:
a: 137.6Å b: 137.6Å c: 184.95Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.216 0.235
Expression system: Trichoplusia ni