PDBe 1z12

X-ray diffraction
2.2Å resolution

Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Vanadate


Function and Biology Details

Reactions catalysed:
A phosphate monoester + H(2)O = an alcohol + phosphate. 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. 

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Low molecular weight phosphotyrosine protein phosphatase Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.95 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
  • Canonical: P11064 (Residues: 2-158; Coverage: 99%)
Gene name: ACP1
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 95.3Å b: 43.4Å c: 41.2Å
α: 90° β: 113.4° γ: 90°
R R work R free
0.173 not available not available
Expression system: Escherichia coli