PDBe 1yzx

X-ray diffraction
1.93Å resolution

Crystal structure of human kappa class glutathione transferase

Released:

Function and Biology Details

Reaction catalysed:
RX + glutathione = HX + R-S-glutathione. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase kappa 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 226 amino acids
Theoretical weight: 25.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y2Q3 (Residues: 1-226; Coverage: 100%)
Gene names: GSTK1, HDCMD47P
Sequence domains: DSBA-like thioredoxin domain
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: C2
Unit cell:
a: 98.275Å b: 118.274Å c: 52.591Å
α: 90° β: 102.67° γ: 90°
R-values:
R R work R free
0.182 0.18 0.204
Expression system: Escherichia coli BL21(DE3)