Function and Biology

Crystal structure of the human Notch 1 ankyrin domain

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF12796
Domain description: Ankyrin repeats (3 copies)
Occurring in:
  1. Notch 1 intracellular domain
The deposited structure of PDB entry 1yyh contains 4 copies of Pfam domain PF12796 (Ankyrin repeats (3 copies)) in Notch 1 intracellular domain. Showing 2 copies in chain A.

PF13637
Domain description: Ankyrin repeats (many copies)
Occurring in:
  1. Notch 1 intracellular domain
The deposited structure of PDB entry 1yyh contains 2 copies of Pfam domain PF13637 (Ankyrin repeats (many copies)) in Notch 1 intracellular domain. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002110
Domain description: Ankyrin repeat
Occurring in:
  1. Notch 1 intracellular domain
IPR036770
Domain description: Ankyrin repeat-containing domain superfamily
Occurring in:
  1. Notch 1 intracellular domain

Structure domain

CATH CATH domain
1.25.40.20
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Ankyrin repeat-containing domain
Occurring in:
  1. Notch 1 intracellular domain
The deposited structure of PDB entry 1yyh contains 2 copies of CATH domain 1.25.40.20 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Notch 1 intracellular domain. Showing 1 copy in chain A.