› › Function and Biology

The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with an EBNA1 peptide

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

Quick links

EC 3.4.19.12: Ubiquitinyl hydrolase 1

Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
  • Ubiquitin C-terminal hydrolase
  • Ubiquitin carboxyl-terminal hydrolase
  • Ubiquitin thiolesterase
  • Yeast ubiquitin hydrolase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00917
Domain description: MATH domain
Occurring in:
  1. Ubiquitin carboxyl-terminal hydrolase 7
The deposited structure of PDB entry 1yy6 contains 1 copy of Pfam domain PF00917 (MATH domain) in Ubiquitin carboxyl-terminal hydrolase 7. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002083
Domain description: MATH/TRAF domain
Occurring in:
  1. Ubiquitin carboxyl-terminal hydrolase 7
IPR008974
Domain description: TRAF-like
Occurring in:
  1. Ubiquitin carboxyl-terminal hydrolase 7

Structure domain

CATH CATH domain
2.60.210.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Homology: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Occurring in:
  1. Ubiquitin carboxyl-terminal hydrolase 7
The deposited structure of PDB entry 1yy6 contains 1 copy of CATH domain 2.60.210.10 (Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A) in Ubiquitin carboxyl-terminal hydrolase 7. Showing 1 copy in chain A.

Quick links