PDBe 1yvl

X-ray diffraction
3Å resolution

Structure of Unphosphorylated STAT1

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero octamer
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
5-residue peptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 741 Da
Source organism: Synthetic construct
Expression system: Not provided
Signal transducer and activator of transcription 1-alpha/beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 683 amino acids
Theoretical weight: 80.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42224 (Residues: 1-683; Coverage: 91%)
Gene name: STAT1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P6122
Unit cell:
a: 102.553Å b: 102.553Å c: 646.481Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.24 0.281
Expression systems:
  • Not provided
  • Escherichia coli