PDBe 1yp0

X-ray diffraction
1.5Å resolution

Structure of the steroidogenic factor-1 ligand binding domain bound to phospholipid and a SHP peptide motif


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor subfamily 0 group B member 2 Chain: B
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.31 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
  • Canonical: P97947 (Residues: 17-28; Coverage: 5%)
Gene names: Nr0b2, Shp
Steroidogenic factor 1 Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P33242 (Residues: 223-461; Coverage: 52%)
Gene names: Ftzf1, Nr5a1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: P41212
Unit cell:
a: 73.175Å b: 73.175Å c: 115.731Å
α: 90° β: 90° γ: 90°
R R work R free
0.223 0.223 0.231
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)