Assemblies
Assembly Name:
Beta-secretase 1 and peptide
Multimeric state:
hetero dimer
Accessible surface area:
16055.53 Å2
Buried surface area:
1313.77 Å2
Dissociation area:
656.88
Å2
Dissociation energy (ΔGdiss):
-0.27
kcal/mol
Dissociation entropy (TΔSdiss):
6.09
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157547
Assembly Name:
Beta-secretase 1 and peptide
Multimeric state:
hetero dimer
Accessible surface area:
16052.78 Å2
Buried surface area:
1296.45 Å2
Dissociation area:
648.22
Å2
Dissociation energy (ΔGdiss):
-0.53
kcal/mol
Dissociation entropy (TΔSdiss):
6.09
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157547
Assembly Name:
Beta-secretase 1 and peptide
Multimeric state:
hetero dimer
Accessible surface area:
16070.79 Å2
Buried surface area:
1296.91 Å2
Dissociation area:
648.46
Å2
Dissociation energy (ΔGdiss):
-2.1
kcal/mol
Dissociation entropy (TΔSdiss):
6.11
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157547
Macromolecules
Chains: A, B, C
Length: 408 amino acids
Theoretical weight: 45.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Eukaryotic aspartyl protease
InterPro:
SCOP: Pepsin-like
Length: 408 amino acids
Theoretical weight: 45.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P56817 (Residues: 48-453; Coverage: 85%)
Pfam: Eukaryotic aspartyl protease
InterPro:
- Aspartic peptidase domain superfamily
- Aspartic peptidase A1 family
- Memapsin-like
- Peptidase family A1 domain
- Aspartic peptidase, active site
- Beta-secretase BACE1
- Beta-secretase BACE
SCOP: Pepsin-like
Chains: X, Y, Z
Length: 5 amino acids
Theoretical weight: 643 Da
Source organism: Homo sapiens
Expression system: Not provided
Length: 5 amino acids
Theoretical weight: 643 Da
Source organism: Homo sapiens
Expression system: Not provided
