PDBe 1ym3

X-ray diffraction
1.75Å resolution

Crystal Structure of carbonic anhydrase RV3588c from Mycobacterium tuberculosis

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 215 amino acids
Theoretical weight: 22.77 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPJ9 (Residues: 2-207; Coverage: 100%)
Gene names: Rv3588c, canB, cynT, mtcA2
Sequence domains: Carbonic anhydrase
Structure domains: Beta-carbonic Anhydrase; Chain A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P41212
Unit cell:
a: 56.377Å b: 56.377Å c: 104.192Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.229
Expression system: Escherichia coli