PDBe 1ylk

X-ray diffraction
2Å resolution

Crystal Structure of Rv1284 from Mycobacterium tuberculosis in Complex with Thiocyanate

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-carbonic anhydrase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 172 amino acids
Theoretical weight: 19.26 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPJ7 (Residues: 2-163; Coverage: 99%)
Gene names: MTCY373.03, Rv1284, canA, mtcA1
Sequence domains: Carbonic anhydrase
Structure domains: Beta-carbonic Anhydrase; Chain A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: F222
Unit cell:
a: 100.164Å b: 154.074Å c: 156.943Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.226
Expression system: Escherichia coli