Function and Biology

Crystal Structure of the Human EB1 C-terminal Dimerization Domain

Source organism: Homo sapiens
Biochemical function: microtubule binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF03271
Domain description: EB1-like C-terminal motif
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1
The deposited structure of PDB entry 1yig contains 2 copies of Pfam domain PF03271 (EB1-like C-terminal motif) in Microtubule-associated protein RP/EB family member 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004953
Domain description: EB1, C-terminal
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1
IPR036133
Domain description: EB1, C-terminal domain superfamily
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1
IPR027328
Domain description: Microtubule-associated protein RP/EB
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1

Structure domain

CATH CATH domain
1.20.5.1430
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1
The deposited structure of PDB entry 1yig contains 2 copies of CATH domain 1.20.5.1430 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Microtubule-associated protein RP/EB family member 1. Showing 1 copy in chain A.
SCOP SCOP annotation
140613
Class: All alpha proteins
Fold: EB1 dimerisation domain-like
Superfamily: EB1 dimerisation domain-like
Occurring in:
  1. Microtubule-associated protein RP/EB family member 1
The deposited structure of PDB entry 1yig contains 2 copies of SCOP domain 140613 (EB1 dimerisation domain-like) in Microtubule-associated protein RP/EB family member 1. Showing 1 copy in chain A.