PDBe 1ygh

X-ray diffraction
1.9Å resolution

HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone acetyltransferase GCN5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 164 amino acids
Theoretical weight: 19.25 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q03330 (Residues: 99-262; Coverage: 37%)
Gene names: ADA4, GCN5, SWI9, YGR252W
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 40.04Å b: 66.51Å c: 80.19Å
α: 90° β: 97.71° γ: 90°
R-values:
R R work R free
0.195 0.195 0.236
Expression system: Escherichia coli BL21(DE3)