› 1yge

X-ray diffraction
1.4Å resolution

LIPOXYGENASE-1 (SOYBEAN) AT 100K

Released:
DOI: 10.2210/pdb1yge/pdb
PDB entry 1yge coloured by chain, front view.
PDB entry 1yge coloured by chain, side view.
PDB entry 1yge coloured by chain, top view.
Source organism: Glycine max
Primary publication:
Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Minor W, Steczko J, Stec B, Otwinowski Z, Bolin JT, Walter R, Axelrod B
Biochemistry 35 10687-701 (1996)
PMID: 8718858

Function and Biology Details

Reaction catalysed: 
Alpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139953 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Seed linoleate 13S-lipoxygenase-1 Chain: A
Molecule details ›
Chain: A
Length: 839 amino acids
Theoretical weight: 94.48 KDa
Source organism: Glycine max
UniProt:
  • Canonical: P08170 (Residues: 1-839; Coverage: 100%)
Gene names: LOX1, LOX1.1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FE 1 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 94.9Å b: 94Å c: 49.9Å
α: 90° β: 90.1° γ: 90°
R-values:
R R work R free
0.197 0.197 0.243

Quick links

Citations

28 review citations

Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology.
Buczynski et al. (2009)
27 more

31 mentions without citation

Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15).
Ivanov et al. (2015)
30 more