PDBe 1ycs

X-ray diffraction
2.2Å resolution

P53-53BP2 COMPLEX

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 199 amino acids
Theoretical weight: 22.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04637 (Residues: 94-292; Coverage: 51%)
Gene names: P53, TP53
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
Apoptosis-stimulating of p53 protein 2 Chain: B
Molecule details ›
Chain: B
Length: 239 amino acids
Theoretical weight: 26.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13625 (Residues: 892-925, 926-1128; Coverage: 21%)
Gene names: ASPP2, BBP, TP53BP2
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 68.8Å b: 72.8Å c: 119Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.205 0.286
Expression system: Escherichia coli