GO terms
Biochemical function:
Biological process:
- negative regulation of endothelial cell apoptotic process
- positive regulation of signaling receptor activity
- positive regulation of vascular associated smooth muscle cell proliferation
- negative regulation of vascular associated smooth muscle cell proliferation
- positive regulation of sprouting angiogenesis
- regulation of complement-dependent cytotoxicity
- negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
- regulation of response to wounding
- positive regulation of miRNA transcription
- positive regulation of plasma cell differentiation
- interleukin-10-mediated signaling pathway
- liver regeneration
- endothelial cell apoptotic process
- negative regulation of chemokine (C-C motif) ligand 5 production
- cellular response to estradiol stimulus
- cellular response to lipopolysaccharide
- branching involved in labyrinthine layer morphogenesis
- negative regulation of cytokine activity
- response to glucocorticoid
- positive regulation of DNA-binding transcription factor activity
- negative regulation of membrane protein ectodomain proteolysis
- regulation of synapse organization
- negative regulation of inflammatory response
- positive regulation of receptor signaling pathway via JAK-STAT
- positive regulation of transcription by RNA polymerase II
- negative regulation of mitotic cell cycle
- positive regulation of DNA-templated transcription
- positive regulation of cell cycle
- positive regulation of MHC class II biosynthetic process
- negative regulation of MHC class II biosynthetic process
- regulation of isotype switching
- negative regulation of nitric oxide biosynthetic process
- negative regulation of neuron apoptotic process
- negative regulation of apoptotic process
- positive regulation of macrophage activation
- defense response to protozoan
- defense response to bacterium
- negative regulation of T cell proliferation
- B cell proliferation
- type 2 immune response
- cellular response to hepatocyte growth factor stimulus
- response to carbon monoxide
- positive regulation of heterotypic cell-cell adhesion
- negative regulation of heterotypic cell-cell adhesion
- response to insulin
- negative regulation of tumor necrosis factor production
- negative regulation of interleukin-8 production
- negative regulation of interleukin-6 production
- negative regulation of interleukin-18 production
- negative regulation of interleukin-12 production
- negative regulation of interleukin-1 production
- negative regulation of type II interferon production
- negative regulation of interferon-alpha production
- response to lipopolysaccharide
- negative regulation of B cell proliferation
- negative regulation of myeloid dendritic cell activation
- leukocyte chemotaxis
- B cell differentiation
- hemopoiesis
- response to inactivity
- response to activity
- negative regulation of autophagy
- regulation of gene expression
- response to organic substance
- response to xenobiotic stimulus
- negative regulation of cell population proliferation
- cytoplasmic sequestering of NF-kappaB
- immune response
- positive regulation of B cell apoptotic process
- negative regulation of chronic inflammatory response to antigenic stimulus
- negative regulation of cytokine production involved in immune response
- positive regulation of immunoglobulin production
- chronic inflammatory response to antigenic stimulus
- response to molecule of bacterial origin
- positive regulation of endothelial cell proliferation
- positive regulation of cytokine production
- negative regulation of cytokine production
- regulation of cytokine production
Protein families (Pfam)![The deposited structure of PDB entry 1y6k contains 1 copy of Pfam domain PF01108 (Tissue factor) in Interleukin-10 receptor subunit alpha. Showing 1 copy in chain B [auth R].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_2_R_Pfam_PF01108_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 1 copy of Pfam domain <span class='highlight'>PF01108 (Tissue factor)</span> in <span class='highlight'>Interleukin-10 receptor subunit alpha</span>. Showing 1 copy in chain <span class='highlight'>B [auth R]</span>.")
![The deposited structure of PDB entry 1y6k contains 1 copy of Pfam domain PF00726 (Interleukin 10) in Interleukin-10. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_1_L_Pfam_PF00726_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 1 copy of Pfam domain <span class='highlight'>PF00726 (Interleukin 10)</span> in <span class='highlight'>Interleukin-10</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")
InterPro annotations
CATH domains![The deposited structure of PDB entry 1y6k contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Interleukin-10 receptor subunit alpha. Showing 2 copies in chain B [auth R].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_2_R_CATH_2.60.40.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.10 (Immunoglobulin-like)</span> in <span class='highlight'>Interleukin-10 receptor subunit alpha</span>. Showing 2 copies in chain <span class='highlight'>B [auth R]</span>.")
![The deposited structure of PDB entry 1y6k contains 1 copy of CATH domain 1.20.1250.10 (Growth Hormone; Chain: A;) in Interleukin-10. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_1_L_CATH_1.20.1250.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 1 copy of CATH domain <span class='highlight'>1.20.1250.10 (Growth Hormone; Chain: A;)</span> in <span class='highlight'>Interleukin-10</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")
SCOP annotations![The deposited structure of PDB entry 1y6k contains 2 copies of SCOP domain 49266 (Fibronectin type III) in Interleukin-10 receptor subunit alpha. Showing 2 copies in chain B [auth R].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_2_R_SCOP_49266_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 2 copies of SCOP domain <span class='highlight'>49266 (Fibronectin type III)</span> in <span class='highlight'>Interleukin-10 receptor subunit alpha</span>. Showing 2 copies in chain <span class='highlight'>B [auth R]</span>.")
![The deposited structure of PDB entry 1y6k contains 1 copy of SCOP domain 47305 (Interferons/interleukin-10 (IL-10)) in Interleukin-10. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1y6k_1_L_SCOP_47305_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1y6k</span> contains 1 copy of SCOP domain <span class='highlight'>47305 (Interferons/interleukin-10 (IL-10))</span> in <span class='highlight'>Interleukin-10</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")