PDBe 1y0m

X-ray diffraction
1.2Å resolution

Crystal structure of of the SH3 domain of phospholipase C Gamma-1

Released:
Source organism: Rattus norvegicus
Entry authors: Mariuzza R, Sangwoo C

Function and Biology Details

Reaction catalysed:
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.17 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10686 (Residues: 791-851; Coverage: 5%)
Gene name: Plcg1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21
Unit cell:
a: 28.748Å b: 30.978Å c: 29.753Å
α: 90° β: 92.12° γ: 90°
R-values:
R R work R free
0.153 0.151 0.177
Expression system: Escherichia coli