PDBe 1y0j

Solution NMR

Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Zinc finger protein ush Chain: B
Molecule details ›
Chain: B
Length: 36 amino acids
Theoretical weight: 3.96 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9VPQ6 (Residues: 202-235; Coverage: 3%)
Gene names: CG2762, ush
Erythroid transcription factor Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 5.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17679 (Residues: 200-243; Coverage: 11%)
Gene names: Gata1, Gf-1
Sequence domains: GATA zinc finger

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing molecular dynamics torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)