PDBe 1xzx

X-ray diffraction
2.5Å resolution

Thyroxine-Thyroid Hormone Receptor Interactions


Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Thyroid hormone receptor beta Chain: X
Molecule details ›
Chain: X
Length: 281 amino acids
Theoretical weight: 31.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P10828 (Residues: 202-461; Coverage: 56%)
Gene names: ERBA2, NR1A2, THR1, THRB
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P3121
Unit cell:
a: 68.764Å b: 68.764Å c: 130.943Å
α: 90° β: 90° γ: 120°
R R work R free
0.191 0.185 0.244
Expression system: Escherichia coli