PDBe 1xx2

X-ray diffraction
1.88Å resolution

Refinement of P99 beta-lactamase from Enterobacter cloacae

Released:
Source organism: Enterobacter cloacae
Entry authors: Knox JR, Sun T

Function and Biology Details

Reaction catalysed:
A beta-lactam + H(2)O = a substituted beta-amino acid. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactamase Chains: A, B
Molecule details ›
Chains: A, B
Length: 361 amino acids
Theoretical weight: 39.27 KDa
Source organism: Enterobacter cloacae
UniProt:
  • Canonical: P05364 (Residues: 21-381; Coverage: 100%)
Gene name: ampC
Sequence domains: Beta-lactamase
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 46.5Å b: 83.47Å c: 95.46Å
α: 90° β: 90.01° γ: 90°
R-values:
R R work R free
0.175 0.175 0.214