PDBe 1xqs

X-ray diffraction
2.9Å resolution

Crystal structure of the HspBP1 core domain complexed with the fragment of Hsp70 ATPase domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hsp70-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 280 amino acids
Theoretical weight: 31.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NZL4 (Residues: 87-362; Coverage: 76%)
Gene names: HSPBP, HSPBP1, PP1845
Structure domains: Leucine-rich Repeat Variant
Heat shock 70 kDa protein 1A Chains: C, D
Molecule details ›
Chains: C, D
Length: 191 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DMV8 (Residues: 184-371; Coverage: 29%)
Gene names: HSP72, HSPA1, HSPA1A, HSX70
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 73.484Å b: 94.809Å c: 155.704Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.296
Expression system: Escherichia coli