PDBe 1xo7

X-ray diffraction
1.61Å resolution

Crystal structure of cyclophilin from Trypanosoma cruzi

Released:
Source organism: Trypanosoma cruzi
Entry authors: Caruthers JM, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 166 amino acids
Theoretical weight: 18.06 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4DPB9 (Residues: 30-194; Coverage: 99%)
Gene name: Tc00.1047053508577.140
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P1
Unit cell:
a: 53.314Å b: 62.142Å c: 64.638Å
α: 109.55° β: 104.21° γ: 104.92°
R-values:
R R work R free
0.179 0.179 0.198
Expression system: Escherichia coli