PDBe 1xmj

X-ray diffraction
2.3Å resolution

Crystal structure of human deltaF508 human NBD1 domain with ATP


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Cystic fibrosis transmembrane conductance regulator Chain: A
Molecule details ›
Chain: A
Length: 290 amino acids
Theoretical weight: 32.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P13569 (Residues: 388-678; Coverage: 20%)
  • Best match: P13569-2 (Residues: 403-617)
Gene names: ABCC7, CFTR
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P43212
Unit cell:
a: 59.793Å b: 59.793Å c: 144.398Å
α: 90° β: 90° γ: 90°
R R work R free
0.248 0.22 0.287
Expression system: Escherichia coli