PDBe 1xkg

X-ray diffraction
1.61Å resolution

Crystal structure of the major house dust mite allergen Der p 1 in its pro form at 1.61 A resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Peptidase 1 Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 35.42 KDa
Source organism: Dermatophagoides pteronyssinus
Expression system: Komagataella pastoris
  • Canonical: P08176 (Residues: 19-320; Coverage: 100%)
Gene name: DERP1
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 64.659Å b: 66.557Å c: 73.388Å
α: 90° β: 90° γ: 90°
R R work R free
0.154 0.153 0.186
Expression system: Komagataella pastoris