PDBe 1xjd

X-ray diffraction
2Å resolution

Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C theta type Chain: A
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 40.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q04759 (Residues: 362-706; Coverage: 49%)
Gene names: PRKCQ, PRKCT
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2
Unit cell:
a: 139.566Å b: 42.4Å c: 67.678Å
α: 90° β: 116.24° γ: 90°
R-values:
R R work R free
0.201 0.201 0.216
Expression system: Escherichia coli BL21(DE3)