PDBe 1x9h

X-ray diffraction
1.5Å resolution

Crystal structure of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum in complex with fructose 6-phosphate

Released:

Function and Biology Details

Reactions catalysed:
D-glucose 6-phosphate = D-fructose 6-phosphate. 
D-mannose 6-phosphate = D-fructose 6-phosphate. 
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional phosphoglucose/phosphomannose isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 302 amino acids
Theoretical weight: 33.59 KDa
Source organism: Pyrobaculum aerophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ZWV0 (Residues: 1-302; Coverage: 100%)
Gene name: PAE1610
Sequence domains: Bacterial phospho-glucose isomerase C-terminal SIS domain
Structure domains: Glucose-6-phosphate isomerase like protein; domain 1

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 55.2Å b: 100.8Å c: 55.9Å
α: 90° β: 113.4° γ: 90°
R-values:
R R work R free
0.153 0.152 0.18
Expression system: Escherichia coli