Structure analysis

The Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution

X-ray diffraction
1.14Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 8700 Å2
Buried surface area: 1000 Å2
Dissociation area: 400 Å2
Dissociation energy (ΔGdiss): -1 kcal/mol
Dissociation entropy (TΔSdiss): 10 kcal/mol
Interface energy (ΔGint): -9 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B
Length: 69 amino acids
Theoretical weight: 7.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P56945 (Residues: 3-71; Coverage: 8%)
Gene names: BCAR1, CAS, CASS1, CRKAS
Pfam: SH3 domain
InterPro:
CATH: SH3 Domains

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