PDBe 1wyx

X-ray diffraction
1.14Å resolution

The Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Breast cancer anti-estrogen resistance protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 69 amino acids
Theoretical weight: 7.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P56945 (Residues: 3-71; Coverage: 8%)
Gene names: BCAR1, CAS, CASS1, CRKAS
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P21
Unit cell:
a: 38.071Å b: 56.193Å c: 37.924Å
α: 90° β: 116.22° γ: 90°
R-values:
R R work R free
0.177 0.176 0.191
Expression system: Escherichia coli