PDBe 1wd8

X-ray diffraction
2.8Å resolution

Calcium free form of human peptidylarginine deiminase type4 (PAD4)

Released:
Source organism: Homo sapiens
Primary publication:
Structural basis for Ca(2+)-induced activation of human PAD4.
Nat. Struct. Mol. Biol. 11 777-83 (2004)
PMID: 15247907

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-arginine deiminase type-4 Chain: A
Molecule details ›
Chain: A
Length: 670 amino acids
Theoretical weight: 74.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UM07 (Residues: 1-663; Coverage: 100%)
Gene names: PAD4, PADI4, PADI5, PDI5
Sequence domains:
Structure domains: Pentein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: C2
Unit cell:
a: 144.612Å b: 60.437Å c: 113.488Å
α: 90° β: 123.61° γ: 90°
R-values:
R R work R free
0.234 0.231 0.264
Expression system: Escherichia coli BL21(DE3)