PDBe 1wbp

X-ray diffraction
2.4Å resolution

SRPK1 bound to 9mer docking motif peptide

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SRSF protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 397 amino acids
Theoretical weight: 45.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96SB4 (Residues: 42-655; Coverage: 61%)
Gene name: SRPK1
Sequence domains: Protein kinase domain
Structure domains:
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 1.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96QZ7 (Residues: 1382-1390; Coverage: 1%)
Gene names: AIP3, BAIAP1, BAP1, MAGI1, TNRC19

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6522
Unit cell:
a: 78.68Å b: 78.68Å c: 310.54Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.247
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided