PDBe 1waa

X-ray diffraction
1.8Å resolution

IG27 protein domain

Released:
Source organism: Homo sapiens
Primary publication:
Mechanical network in titin immunoglobulin from force distribution analysis.
OpenAccess logo PLoS Comput. Biol. 5 e1000306 (2009)
PMID: 19282960

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Titin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 93 amino acids
Theoretical weight: 10.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 12677-12765; Coverage: 0%)
Gene name: TTN
Structure domains: Immunoglobulins
Titin Chain: E
Molecule details ›
Chain: E
Length: 93 amino acids
Theoretical weight: 10.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 12677-12765; Coverage: 0%)
Gene name: TTN
Structure domains: Immunoglobulins
Titin Chain: F
Molecule details ›
Chain: F
Length: 93 amino acids
Theoretical weight: 10.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 12677-12765; Coverage: 0%)
Gene name: TTN
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P212121
Unit cell:
a: 62.24Å b: 75.99Å c: 134.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.207 0.268
Expression system: Escherichia coli