Function and Biology Details
Reaction catalysed:
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Synaptojanin-1 and AP-2 complex subunit alpha-2 (preferred)
PDBe Complex ID:
PDB-CPX-128924 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
AP-2 complex subunit alpha-2
Molecule details ›
Chain: A
Length: 250 amino acids
Theoretical weight: 28.05 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 250 amino acids
Theoretical weight: 28.05 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P17427 (Residues: 690-938; Coverage: 27%)
Sequence domains:
Structure domains:
Synaptojanin-1
Molecule details ›
Chain: P
Length: 12 amino acids
Theoretical weight: 1.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 12 amino acids
Theoretical weight: 1.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: O43426 (Residues: 1477-1488; Coverage: 1%)
Synaptojanin-1
Molecule details ›
Chain: Q
Length: 12 amino acids
Theoretical weight: 1.34 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 12 amino acids
Theoretical weight: 1.34 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: O43426 (Residues: 1458-1469; Coverage: 1%)
