PDBe 1w7j

X-ray diffraction
2Å resolution

Crystal Structure Of Myosin V Motor With Essential Light Chain + ADP-BeFx - Near Rigor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Unconventional myosin-Va Chain: A
Molecule details ›
Chain: A
Length: 795 amino acids
Theoretical weight: 91.61 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q02440 (Residues: 1-792; Coverage: 43%)
Gene name: MYO5A
Sequence domains:
Myosin light chain 6B Chain: B
Molecule details ›
Chain: B
Length: 151 amino acids
Theoretical weight: 17.09 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P14649 (Residues: 58-208; Coverage: 73%)
Gene names: MLC1SA, MYL6B
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2
Unit cell:
a: 169.684Å b: 95.988Å c: 84.306Å
α: 90° β: 96.11° γ: 90°
R-values:
R R work R free
0.196 0.194 0.224
Expression system: Spodoptera frugiperda