PDBe 1w74

X-ray diffraction
2.6Å resolution

X-ray structure of peptidyl-prolyl cis-trans isomerase A, PpiA, Rv0009, from Mycobacterium tuberculosis.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase A Chains: A, B
Molecule details ›
Chains: A, B
Length: 191 amino acids
Theoretical weight: 20.3 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P9WHW3 (Residues: 2-182; Coverage: 100%)
Gene names: MTCY10H4.08, Rv0009, ppiA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P31
Unit cell:
a: 65.349Å b: 65.349Å c: 102.493Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.212 0.229
Expression system: Escherichia coli BL21