PDBe 1w70

X-ray diffraction
1.46Å resolution

SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neutrophil cytosol factor 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 14 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P14598 (Residues: 360-372; Coverage: 3%)
Gene names: NCF1, NOXO2, SH3PXD1A
Neutrophil cytosol factor 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15080 (Residues: 174-228; Coverage: 16%)
Gene names: NCF4, SH3PXD4
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 39.64Å b: 50.49Å c: 68.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.181 0.207
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)