PDBe 1w0o

X-ray diffraction
1.9Å resolution

Vibrio cholerae sialidase

Released:
Source organism: Vibrio cholerae

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sialidase Chain: A
Molecule details ›
Chain: A
Length: 781 amino acids
Theoretical weight: 85.67 KDa
Source organism: Vibrio cholerae
UniProt:
  • Canonical: P0C6E9 (Residues: 1-781; Coverage: 100%)
Gene names: VC_1784, nanH
Sequence domains: Vibrio cholerae sialidase, lectin insertion
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 70.31Å b: 74.91Å c: 151.615Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.179 0.218