PDBe 1v8s

X-ray diffraction
2.2Å resolution

Crystal structure analusis of the ADP-ribose pyrophosphatase complexed with AMP and Mg

Released:

Function and Biology Details

Reaction catalysed:
ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribose pyrophosphatase Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 19.29 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q84CU3 (Residues: 1-170; Coverage: 100%)
Gene name: ndx4
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 49.74Å b: 49.74Å c: 118.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 0.248
Expression system: Escherichia coli BL21(DE3)