› 1v8g

X-ray diffraction
2.1Å resolution

Crystal structure of anthranilate phosphoribosyltransferase (TrpD) from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1v8g/pdb
PDB entry 1v8g coloured by chain, front view.
PDB entry 1v8g coloured by chain, side view.
PDB entry 1v8g coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Shimizu K, Kunishima N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-160763 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anthranilate phosphoribosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 329 amino acids
Theoretical weight: 34.32 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P83827 (Residues: 1-329; Coverage: 100%)
Gene name: trpD
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: C2
Unit cell:
a: 143.318Å b: 72.45Å c: 73.539Å
α: 90° β: 110.36° γ: 90°
R-values:
R R work R free
0.212 0.212 0.255
Expression system: Escherichia coli BL21(DE3)

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