Function and Biology

Solution Structure of the Pleckstrin Homology Domain of Human KIAA0053 Protein

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00169
Domain description: PH domain
Occurring in:
  1. Rho GTPase-activating protein 25
The deposited structure of PDB entry 1v89 contains 1 copy of Pfam domain PF00169 (PH domain) in Rho GTPase-activating protein 25. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001849
Domain description: Pleckstrin homology domain
Occurring in:
  1. Rho GTPase-activating protein 25
IPR045188
Domain description: PH domain containing protein Boi1/Boi2-like
Occurring in:
  1. Rho GTPase-activating protein 25
IPR011993
Domain description: PH-like domain superfamily
Occurring in:
  1. Rho GTPase-activating protein 25

Structure domain

CATH CATH domain
2.30.29.30
Class: Mainly Beta
Architecture: Roll
Topology: PH-domain like
Homology: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Occurring in:
  1. Rho GTPase-activating protein 25
The deposited structure of PDB entry 1v89 contains 1 copy of CATH domain 2.30.29.30 (PH-domain like) in Rho GTPase-activating protein 25. Showing 1 copy in chain A.
SCOP SCOP annotation
50730
Class: All beta proteins
Fold: PH domain-like barrel
Superfamily: PH domain-like
Occurring in:
  1. Rho GTPase-activating protein 25
The deposited structure of PDB entry 1v89 contains 1 copy of SCOP domain 50730 (Pleckstrin-homology domain (PH domain)) in Rho GTPase-activating protein 25. Showing 1 copy in chain A.