PDBe 1v25

X-ray diffraction
2.3Å resolution

Crystal structure of tt0168 from Thermus thermophilus HB8

Released:

Function and Biology Details

Reaction catalysed:
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. 
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Long-chain-fatty-acid--CoA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 541 amino acids
Theoretical weight: 59.65 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SKN9 (Residues: 1-541; Coverage: 100%)
Gene name: TTHA0604
Sequence domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45XU
Spacegroup: P212121
Unit cell:
a: 64.52Å b: 101.151Å c: 176.487Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.204 0.24
Expression system: Escherichia coli