PDBe 1uti

X-ray diffraction
1.5Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GRB2-related adaptor protein 2 Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O89100 (Residues: 265-322; Coverage: 18%)
Gene names: Gads, Grap2, Grb2l, Grid, Mona
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Mitogen-activated protein kinase kinase kinase kinase 1 Chain: D
Molecule details ›
Chain: D
Length: 16 amino acids
Theoretical weight: 1.82 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P70218 (Residues: 465-480; Coverage: 2%)
Gene names: Hpk1, Map4k1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 71.456Å b: 27.442Å c: 33.043Å
α: 90° β: 104.22° γ: 90°
R-values:
R R work R free
0.208 0.207 0.221
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided