› › Structure analysis

Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom

X-ray diffraction
0.66Å resolution
PDB entry 1us0 coloured by chain, front view.
PDB entry 1us0 coloured by chain, side view.
PDB entry 1us0 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Aldo-keto reductase family 1 member B1
hide full assembly name
Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-147224

Macromolecules

Aldo-keto reductase family 1 member B1
Chain: A
Length: 316 amino acids
Theoretical weight: 35.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15121 (Residues: 1-316; Coverage: 100%)
Gene names: AKR1B1, ALDR1, ALR2
Pfam: Aldo/keto reductase family
InterPro:
CATH: NADP-dependent oxidoreductase domain
SCOP: Aldo-keto reductases (NADP)
Aldo-keto reductase family 1 member B1 in PDB entry 1us0, assembly 1, front view.
Aldo-keto reductase family 1 member B1 in PDB entry 1us0, assembly 1, side view.
Aldo-keto reductase family 1 member B1 in PDB entry 1us0, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links