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HR1b domain from PRK1

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: signal transduction
Cellular component: not assigned

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EC 2.7.11.13: Protein kinase C

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (diacylglycerol-dependent)
Alternative Name(s):
  • CPKC
  • CPKC-alpha
  • CPKC-beta
  • CPKC-gamma
  • Calcium-dependent protein kinase C
  • Calcium-independent protein kinase C
  • Calcium/phospholipid dependent protein kinase
  • NPKC
  • NPKC-delta
  • NPKC-epsilon
  • NPKC-eta
  • NPKC-theta
  • PKC
  • PKC-alpha
  • PKC-beta
  • PKC-delta
  • PKC-epsilon
  • PKC-gamma
  • PKC-zeta
  • Pkc1p
  • Protein kinase C-epsilon
  • STK24

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF02185
Domain description: Hr1 repeat
Occurring in:
  1. Serine/threonine-protein kinase N1
The deposited structure of PDB entry 1urf contains 1 copy of Pfam domain PF02185 (Hr1 repeat) in Serine/threonine-protein kinase N1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR011072
Domain description: HR1 rho-binding domain
Occurring in:
  1. Serine/threonine-protein kinase N1
IPR036274
Domain description: HR1 repeat superfamily
Occurring in:
  1. Serine/threonine-protein kinase N1
IPR037317
Domain description: Serine/threonine-protein kinase N1, second HR1 domain
Occurring in:
  1. Serine/threonine-protein kinase N1

Structure domain

CATH CATH domain
1.10.287.160
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: HR1 repeat
Occurring in:
  1. Serine/threonine-protein kinase N1
The deposited structure of PDB entry 1urf contains 1 copy of CATH domain 1.10.287.160 (Helix Hairpins) in Serine/threonine-protein kinase N1. Showing 1 copy in chain A.
SCOP SCOP annotation
46586
Class: All alpha proteins
Fold: Long alpha-hairpin
Superfamily: HR1 repeat
Occurring in:
  1. Serine/threonine-protein kinase N1
The deposited structure of PDB entry 1urf contains 1 copy of SCOP domain 46586 (HR1 repeat) in Serine/threonine-protein kinase N1. Showing 1 copy in chain A.

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